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Melanogenesis is a complex multistep process of high molecular weight melanins production by hydroxylation and polymerization of polyphenols. Melanins have a wide range of applications other than being a sun - protection pigment. Melanogenesis pathway exists from prokaryotes to eukaryotes. It has evolved over years owing to the fact that the melanin pigment(More)
─ Supersonic flows associated with missiles, aircraft, missile engine intake and rocket nozzles are often steady. The shape of the nozzle geometry is increasingly attractive in heating, ventilation and air conditioning applications. The objective of the present work is to simulate and understand Supersonic flows with twin free jet Flow at various Mach(More)
These are exciting times for bioinformaticians, computational biologists and drug designers with the genome and proteome sequences and related structural databases growing at an accelerated pace. The post-genomic era has triggered high expectations for a rapid and successful treatment of diseases. However, in this biological information rich and functional(More)
Vitiligo is an idiopathic disorder characterized by depigmented patches on the skin due to progressive loss of melanocytes. Several genetic, immunological, and pathophysiological investigations have established vitiligo as a polygenetic disorder with multifactorial etiology. However, no definite model explaining the interplay between these causative factors(More)
In this paper the supersonic combustion of hydrogen using strut injector along with two-dimensional turbulent non-premixed combustion model. The present work is based on the standard k-ε which has been used for modeling the turbulence and single step finite rate chemistry. In this process, a PDF (Probability Density Function) approach is created and this(More)
Network-based approaches to human disease have diverse biological and clinical applications. A more appropriate interpretation of biological interconnectivity with disease progression could possibly lead to identification of disease pathways and disease genes. This, in turn, helps in accurate prediction of biomarkers and targets for drug development. This(More)
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