Khurram Mir

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BACKGROUND It is increasingly recognised that, in cancer patients, disease progression is dependent on a complex interaction of the tumour and the host inflammatory response and that the systemic inflammatory response, as evidenced by an elevated C-reactive protein (CRP) concentration, may be a useful prognostic factor. MATERIALS AND METHODS The(More)
OBJECTIVE To determine the long-term objective and subjective outcome of patients with benign prostatic enlargement (BPE) treated by endoscopic laser ablation of the prostate (ELAP), as part of a multicentre randomized controlled trial of ELAP against TURP. PATIENTS AND METHODS Initially, 151 patients with BPE were randomized to undergo either ELAP or(More)
A 25-year-old man with no urinary symptoms was referred with microscopic haematuria. Renal tract ultrasound showed normal kidneys and a mixed echogenic mass within the pelvis on the right side indenting and protruding into the bladder with a nipple shaped appearance and measuring 4.9• cm (Fig. 1). Subsequent IVU confirmed a large, smooth filling defect on(More)
OBJECTIVE To assess the relationships among circulating insulin-like growth factor-1 (IGF-1), IGF binding protein-3 (IGFBP-3), prostate-specific antigen (PSA) and C-reactive protein (an indicator of inflammatory systemic response) in patients with prostate disease and cancer of different stages. PATIENTS AND METHODS Circulating IGF-1, IGFBP-3, PSA and(More)
OBJECTIVE To relate the repeat length of the androgen-receptor CAG trinucleotide to the age of onset of prostate cancer, stage and grade of disease. PATIENTS AND METHODS After obtaining ethical approval, 265 patients with locally confined or locally advanced/metastatic prostate cancer were identified and evaluated for age at diagnosis (< 65 years and > 75(More)
A forty-year-old African male residing in the United Kingdom presented with a year's history of progressively increasing painful bilateral lower limb oedema intially involving the feet and gradually extending to both legs. The swelling was non-pitting, and the pretibial skin contained dark pigmented areas (Fig. 1). Six months later he developed multiple(More)
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