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This paper presents an approach to the automatic placement of a combination of macro blocks and standard cells. Standard cells are partitioned into flexible virtual blocks during block placement and are later placed into the target area through an integrated optimization routine. Results for a number of examples are given, including those from standard(More)
Human parvovirus B19 has been described as a causative agent of erythema infectiosum (a disease common in children), aplastic crisis in patients with hemolytic disorders, and arthralgias and arthritis. Joint involvement may be a prominent clinical feature of parvovirus B19 infection and may last for several weeks. We describe three cases of acute bilateral(More)
The activities of cefepime and amikacin alone or in combination against an isogenic pair of Enterobacter cloacae strains (wild type and stably derepressed, ceftazidime-resistant mutant) were compared using an experimental model of pneumonia in non-leucopenic rats. Animals were infected by administering 8.4 log10 cfu of E. cloacae intratracheally, and(More)
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