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PURPOSE To present revised criteria for the diagnosis of Vogt-Koyanagi-Harada disease, a chronic, bilateral, granulomatous ocular and multisystem inflammatory condition of unknown cause. METHODS Diagnostic criteria and nomenclature were subjects of discussion at the First International Workshop on Vogt-Koyanagi-Harada Disease on October 19-21, 1999, at(More)
We recently identified a trinucleotide repeat polymorphism, (GCT)n, within the transmembrane (TM) segment of the human MHC class I MICA gene (MHC class I chain-related gene A). Five distinct alleles (A4, A5, A5.1, A6, A9) corresponding to 4, 5, 5 with one nucleotide insertion, 6 and 9 repetitions, respectively, have been detected in various HLA-homozygous B(More)
The prevalence and etiology of visual loss and of eye diseases were determined in the Kingdom of Saudi Arabia. The sample was a stratified geographic cluster sample of 14,577 persons representing the settled population of Saudi Arabia. A nonstatistical sample of 2,233 bedouins was also examined. The survey revealed that 1.5% of the population are blind and(More)
PURPOSE To present a case of ligneous conjunctivitis where the recurrence of membranous conjunctivitis was prevented by subconjunctival and topical instillation of fresh frozen plasma. DESIGN Interventional case report. METHODS A case of ligneous conjunctivitis with multiple recurrences since the age of 3 years developed recurrent membranous(More)
AIMS AND BACKGROUND The main objective of this study was to determine the causes of uveitis at a referral center in Riyadh, Saudi Arabia. METHODS We carried out a retrospective review of clinical records of 200 uveitis cases referred to The Eye Center, a referral center in Riyadh, Saudi Arabia. There were 120 (60%) males and 80 (40%) females with an age(More)
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease. Ocular complications occur in up to one-third of patients with SLE. The ocular findings may represent the initial manifestation of the disease and may lead to severe ocular morbidity and loss of vision. Early diagnosis and prompt management of patients with SLE are mandatory and(More)
PURPOSE To assess the outcome of retinal vasculitis in patients with Behçet disease treated with infliximab compared to treatment with conventional therapy. DESIGN Nonrandomized, retrospective comparative clinical study. METHODS Patients with Behçet disease with all four major criteria were included in this study. Patients had recurrent episodes of(More)
We studied a total of 27 cases of fungal keratitis is Saudi Arabia. History of trauma was found in 9 patients, and previous use of topical steroids in 6 patients. In the majority of patients the onset of the disease was in fall and spring. The most frequent cause of fungal keratitis was found to be Aspergillus spp., and these were isolated from 11 cases(More)