Khalid Arab Awartani

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BACKGROUND Reproductive loss carries immeasurable human costs as well as being costly to the health care system. The objectives of this study were to determine the frequency and distribution of cytogenetically abnormal miscarriages from couples with recurrent miscarriage and to compare the results with the general population. METHODS A total of 420(More)
BACKGROUND To evaluate the relationship between endometrial thickness on day of human chorionic gonadotrophin administration (hCG) and pregnancy outcome in a large number of consecutive in vitro fertilization and embryo transfer (IVF-ET) cycles. METHODS A retrospective cohort study including all patients who had IVF-ET from January 2003-December 2005(More)
Congenital hyperinsulinism is the most common cause of persistent hypoglycaemia in infancy. Early surgical intervention is usually required to prevent brain damage. The prevention of the transmission to the offspring is important in families carrying the mutated gene. Preimplantation genetic diagnosis (PGD) is an early genetic testing procedure for couples(More)
BACKGROUND Obesity is a common disorder with a negative impact on IVF treatment outcome. It is not clear whether morbidly obese women (BMI >= 35 kg/m2) respond to treatment differently as compared to obese women (BMI = 30-34.9 kg/m2) in IVF. Our aim was to compare the outcome of IVF or ICSI treatments in obese patients to that in morbidly obese patients. (More)
OBJECTIVES The aim of this study was to investigate the prognosis in future IVF cycles of patients with empty follicle syndrome (EFS). STUDY DESIGN EFS cases and their future cycles were reviewed. Clinical pregnancy rate per started cycle was taken as the primary outcome in assessing the future outcome in IVF treatment cycles. RESULTS A total of 3023(More)
Polycystic ovary syndrome (PCOS) is a common endocrine condition that affects women of reproductive age. Anovulation, menstrual irregularities, hirsutism, and infertility are common clinical presentations. Long-term health concerns such as type II diabetes mellitus and, possibly, cardiovascular disease, have been linked to PCOS. Metformin, an oral(More)
OBJECTIVES Morquio syndrome is an autosomal recessive disease and mutations in the N-acetylgalactosamine 6-sulfate sulfatase (GALNS) gene cause Morquio type A disease. Preimplantation genetic diagnosis (PGD), an early form of prenatal diagnosis for couples at risk of transmitting inherited diseases, was applied to prevent transmission of this disease. (More)
OBJECTIVE To determine the effect of microsurgical resection and tubocornual anastomosis (TCA) of nonocclusive salpingitis isthmica nodosa (SIN) on fertility and risk for ectopic pregnancy (EP). DESIGN Prospective cohort. SETTING University-affiliated tertiary fertility clinic. PATIENT(S) Infertile women with hysterosalpingography evidence of SIN in(More)
BACKGROUND Elective induction of labour is a common obstetrical practice. Dinoprostone (prostaglandin E2 in triacetin base gel) has been shown to be an effective and fairly safe agent for this purpose in inpatient settings. Currently published work does not assess the effectiveness and safety of dinoprostone in an ambulatory setting. OBJECTIVE To assess(More)
To the Editor: Naturally occurring human knockouts have greatly expanded our understanding of the medical relevance of genes, or lack thereof (1). Indeed, while biallelic inactivation of genes can result in severe Mendelian disorders, other genes seem to be toleratedwhen knocked out (2). We have been studying embryonic lethality as an extreme Mendelian(More)