Khalid Amin Khan

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Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available for clinical consumption in 1962 and was used mainly for urinary tract infections caused by Escherichia coli and other pathogenic Gram-negative bacteria. Recently, significant(More)
The changing trends in information technology have greatly influenced the role of GIS in spatial data management , analysis, processing and presentation. It has evolved from the conventional cartography and image processing to advanced 3D visualization and dynamic graphics tools. Due to this evolving nature of GIS, it has found wide applications in a number(More)
Two important biologically active compounds were isolated from Mallotus philippensis. The isolated compounds were characterized using spectroanalytical techniques and found to be bergenin (1) and 11-O-galloylbergenin (2). The in vitro antioxidant and antiplasmodial activities of the isolated compounds were determined. For the antioxidant potential, three(More)
This paper describes GPS Workstation, a general purpose navigation software which requires a low-cost GPS connected to the computer. It provides an integrated display of positioning data along with satellite positions, their signal strengths and data quality parameters. The software can be used for static point averaging of GPS data to get more precise(More)
An efficient and novel method for the synthesis in moderate to good yield (72%-84%) of a series of 3-amino-1-substituted-9,10-dihydrophenanthrene-2,4-dicarbonitriles 1-5 via one-pot multi-component reactions of aldehydes, malononitrile, 1-tetralone and ammonium acetate has been delineated. Cyclocondensation attempts of aminocyanophenanthrene derivatives 1,(More)
The complete mol-ecule of the title compound, C(14)H(16)N(2)S(2), is generated by a crystallographic inversion centre. The thio-phene residue is close to being coplanar with the imine group [C-C-C-N torsion angle = 6.5 (2)°], and the conformation about the imine C=N bond [1.281 (2) Å] is E. In the crystal, the three-dimensional architecture is consolidated(More)
In the title compound, 2C(24)H(21)N(3)S·C(6)H(6), the two independent Schiff base mol-ecules (A and B) in the asymmetric unit differ in the orientation of the tetra-hydro-benzothio-phene ring system with respect to the carbazole ring system by 180° rotation about the C-C bond in the C-C=N-C linkage. The two mol-ecules also differ in the orientation of the(More)