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  • Jiong Hu, Rüdiger Popp, +5 authors Ingrid Fleming
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2014 (First Published: 3 February 2014)
  • Cytochrome P450 (CYP) epoxygenases generate bioactive lipid epoxides which can be further metabolized to supposedly less active diols by the soluble epoxide hydrolase (sEH). As the role of epoxidesContinue Reading
  • Nicole Mangels, Khader Awwad, Annika Wettenmann, Laila Romagueira Bichara dos Santos, Timo Froemel, Ingrid Fleming
  • Biology, Medicine
  • Prostaglandins & other lipid mediators
  • 2016 (First Published: 1 September 2016)
  • Inhibition or deletion of the soluble epoxide hydrolase (sEH) has been linked to reduced cholesterol and protection against atherosclerosis. This study set out to identify sEH substrate(s) orContinue Reading