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Xiaoxue Wang1,2,†, Dana M. Lord5,†, Hsin-Yao Cheng4,†, Devon O. Osbourne4, Seok Hoon Hong2, Viviana Sanchez-Torres2, Cecilia Quiroga4, Kevin Zheng6, Torsten Herrmann7, Wolfgang Peti5, Michael J. Benedik3, Rebecca Page6,*, and Thomas K. Wood2,3,4,* 1Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology,(More)
Among bacterial toxin-antitoxin systems, to date no antitoxin has been identified that functions by cleaving toxin mRNA. Here we show that YjdO (renamed GhoT) is a membrane lytic peptide that causes ghost cell formation (lysed cells with damaged membranes) and increases persistence (persister cells are tolerant to antibiotics without undergoing genetic(More)
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