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BACKGROUND The objectives of this study were to assess the impact among young men of herpes simplex virus type 2 (HSV-2) status on the acquisition of human immunodeficiency virus (HIV) and on the protective effect of male circumcision against HIV acquisition. METHODS We used data collected during a male circumcision trial conducted in Orange Farm, South(More)
BACKGROUND The aims of the study were to investigate the factors associated with not having breast reconstruction following mastectomy and to assess patient satisfaction with information on reconstruction. PATIENTS AND METHODS We analysed a historical cohort of 1937 consecutive patients who underwent mastectomy at Institut Curie between January 2004 and(More)
BACKGROUND Mounting evidence suggests an association between human papillomavirus (HPV) and HIV acquisition. This study aimed to explore this association among South African female sex workers (FSWs). METHODS We used data from 88 HIV-negative FSWs who participated in a vaginal gel (COL-1492) trial. Cervicovaginal rinse samples, obtained before(More)
OBJECTIVE Little is known about the interaction between human papillomavirus (HPV) and HIV. This study aimed to explore the association of oncogenic (high risk) and nononcogenic (low risk) HPV with HIV incidence. METHODS We used 1683 urethral swabs collected at the last follow-up visit of a male circumcision trial conducted in Orange Farm (South Africa).(More)
BACKGROUND Tako-Tsubo cardiomyopathy (TTC) is a recently described medical entity and the incidence of TTC in a global population is still uncertain. We sought to prospectively assess the incidence of TTC in a large urban area. METHODS AND RESULTS We included all consecutive patients referred for coronary angiography in three hospitals located in Paris(More)
We performed a cost-effectiveness analysis of four vitamin D supplementation strategies for primary prevention of hip fracture among the elderly population and found that the most cost-effective strategy was screening for vitamin D insufficiency followed by adequate treatment to attain a minimum 25(OH) serum level. Vitamin D supplementation has a(More)
BACKGROUND With the development of information and communication technologies, telemedicine has been proposed as a way to improve patient management by facilitating access to appropriate diagnosis and treatment. The Paris Ile de France Regional Health Agency is currently funding a comprehensive program of telemedicine experiments. This article describes the(More)
BACKGROUND Randomized controlled trials (RCTs) for the prevention of HIV heterosexual acquisition are usually conducted among adult African populations with high heterogeneity in individual risk of infection. PURPOSE The objectives were to (a) review how this heterogeneity has been considered when designing and interpreting such RCTs, (b) evaluate its(More)
La prolifération tumorale est une information indispensable pour évaluer aussi bien l’agressivité que la chimiosensibilité des cancers du sein [14]. Ainsi, les tumeurs triples négatives (RH– et HER2–) et les tumeurs avec surexpression ou amplification d’HER2 (HER2+) sont très habituellement des tumeurs avec une prolifération élevée, de mauvais pronostic,(More)
BACKGROUND Few studies have analyzed the cost of treatment of chronic angina pectoris, especially in European countries. AIM To determine, using a modeling approach, the cost of care in 2012 for 1year of treatment of patients with stable angina, according to four therapeutic options: optimal medical therapy (OMT); percutaneous coronary intervention with(More)