Learn More
PURPOSE To determine if the addition of carboplatin chemotherapy to whole brain irradiation improves response and survival in patients with brain metastases from non-small cell lung cancer (NSCLC). PATIENTS AND METHODS Forty-two patients with brain metastases from NSCLC and performance status ECOG 0-2 were randomised to receive either whole brain(More)
OBJECTIVE To examine the efficacy of tonsillectomy in ameliorating symptoms and preventing recurrence of episodes in children with PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis). DESIGN Retrospective case series. SETTING Tertiary care children's hospital. PATIENTS Patients who presented to a major tertiary teaching(More)
PURPOSE At our center, approximately 30% of radical radiotherapy (RRT) candidates become ineligible for RRT for non-small-cell lung cancer (NSCLC) after positron emission tomography (PET). We hypothesized that early cancer death rates would be lower in patients receiving RRT after PET staging compared with conventionally staged patients. METHODS AND(More)
In this report, we describe how to highly optimize a computer unified device architecture based platform to perform real-time processing of optical coherence tomography interferometric data and three-dimensional (3-D) volumetric rendering using a commercially available, cost-effective, graphics processing unit (GPU). The maximum complete attainable axial(More)
OBJECTIVE To determine if there is a dose-response curve for TGF-beta1 in a rabbit calvarial defect model. STUDY DESIGN Controlled animal study using arms of increasing concentrations of TGF-beta1 to evaluate the osteoinductive potential of each arm. METHODS Sixteen skeletally mature New Zealand white rabbits were randomized into control and(More)
BACKGROUND Lower extremity peripheral arterial disease (PAD) is underdiagnosed and undertreated in Canada, although data are limited. We sought to measure PAD prevalence and treatment patterns in ambulatory settings. METHODS Five trained undergraduate pharmacy students screened subjects > 50 years of age in 10 community pharmacies and 4 physician offices(More)
PURPOSE To our knowledge this is the first report of intravesical oncolytic reovirus for therapy of superficial bladder cancer in an orthotopic bladder tumor model. Superficial bladder carcinomas are often multifocal and have high recurrences after surgical resection. In 20% of cases intravesical immunotherapy fails to prevent recurrence and complications(More)
PURPOSE OF REVIEW Microvascular reconstruction for head and neck cancers has improved both cosmesis and functionality of patients undergoing treatment. Many patients have had prior surgery (neck dissection), radiation and/or chemotherapy as part of their management. When microvascular reconstruction is required after previous treatment, finding appropriate(More)