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The functional networks of cultured neurons exhibit complex network properties similar to those found in vivo. Starting from random seeding, cultures undergo significant reorganization during the initial period in vitro, yet despite providing an ideal platform for observing developmental changes in neuronal connectivity, little is known about how a complex(More)
OBJECTIVE To assess the usefulness, compatibility, and long-term operability of a microelectrode array into the median nerve of the left arm of a healthy volunteer, including perception of feedback stimulation and operation of an instrumented prosthetic hand. SETTING The study was carried out from March 14 through June 18, 2002, in England and the United(More)
(2010) Controlling a mobile robot with a biological brain. It is advisable to refer to the publisher's version if you intend to cite from the work. All outputs in CentAUR are protected by Intellectual Property Rights law, including copyright law. Copyright and IPR is retained by the creators or other copyright holders. Terms and conditions for use of this(More)
Deep Brain Stimulation (DBS) has been successfully used throughout the world for the treatment of Parkinson's disease symptoms. To control abnormal spontaneous electrical activity in target brain areas DBS utilizes a continuous stimulation signal. This continuous power draw means that its implanted battery power source needs to be replaced every 18-24(More)
This paper introduces a new robust nonlinear identification algorithm using the predicted residual sums of squares (PRESS) statistic and forward regression. The major contribution is to compute the PRESS statistic within a framework of a forward orthogonalization process and hence construct a model with a good generalization property. Based on the(More)
In this paper, a continuation of a variable radius niche technique called Dynamic Niche Clustering developed by (Gan & Warwick, 1999) is presented. The technique employs a separate dynamic population of overlapping niches that coexists alongside the normal population. An empirical analysis of the updated methodology on a large group of standard optimisation(More)
This paper describes the recent developments and improvements made to the variable radius niching technique called Dynamic Niche Clustering (DNC) originally described in [4] and [5]. DNC employs a separate population of overlapping fuzzy niches with independent radii which operate in the decoded parameter space and are maintained alongside the normal GA(More)