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BACKGROUND Unilateral middle cerebral artery infarction has been reported to impair bilateral hand grasp. METHODS Individuals (5 males and 5 females; age 33-86 years) with chronic unilateral middle cerebral artery stroke (4 right lesions and 6 left lesions) repeatedly lifted a 260-g object. Participants were then trained to lift the object using(More)
In this position paper we explore the application of re-factoring to product line architectures (PLAs). A PLA is a common architecture for a set of closely related products. As the set of products and their features changes, the PLA must evolve as well. A typical problem in managing such evolution is that the overall structure of the PLA slowly but surely(More)
In the United States the preferred method of obtaining dietary intake data is the 24-hour dietary recall, yet the measure of most interest is usual or long-term average daily intake, which is impossible to measure. Thus, usual dietary intake is assessed with considerable measurement error. Also, diet represents numerous foods, nutrients and other(More)
This study presents a subject-specific method of determining the zero-load lengths of the cruciate and collateral ligaments in computational knee modeling. Three cadaver knees were tested in a dynamic knee simulator. The cadaver knees also underwent manual envelope of motion testing to find their passive range of motion in order to determine the zero-load(More)
There has been great public health interest in estimating usual, i.e., long-term average, intake of episodically consumed dietary components that are not consumed daily by everyone, e.g., fish, red meat and whole grains. Short-term measurements of episodically consumed dietary components have zero-inflated skewed distributions. So-called two-part models(More)
F olic acid is a compound that does not occur naturally in food but is added as a fortificant and dietary supplement. When it is ingested it is converted into forms of reduced folate that are identical to those arising from ingestion of naturally occurring folate in foods; however, some folic acid may appear unmetabolized in the serum (1, 2). Very little is(More)
Most statistical methods that adjust analyses for measurement error assume that the target exposure T is a fixed quantity for each individual. However, in many applications, the value of T for an individual varies with time. We develop a model that accounts for such variation, describing the model within the framework of a meta-analysis of validation(More)
To determine the number and distribution of days required to produce stable group-level estimates of a 7 d mean for common accelerometer-derived activity measures. Data from the 2003-2006 NHANES were used in this analysis. The sample included 986 youth (6-19 year) and 2532 adults (⩾20 year) with 7 d of  ⩾10 h of wear. Accelerometer measures included minutes(More)
The development of nutrition and health guidelines and policies requires reliable scientific information. Unfortunately, theoretical considerations and empirical evidence indicate that a large percentage of science-based claims rely on studies that fail to replicate. The session "Strategies to Optimize the Impact of Nutrition Surveys and Epidemiological(More)
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