Kevin S. Zhou

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PURPOSE To determine if the topoisomerase I inhibitor Camptothecin (CPT) can induce apoptosis in vitro in a human nasopharyngeal carcinoma (NPC) cell line with low differentiation (CNE-2Z). METHODS The light microscopy, flow cytometry and agarose gel electrophoresis were used to examine the morphological changes, cell cycle distribution, hypodiploid cells(More)
To segment spinal canals is desirable in many studies because it facilitates analysis, diagnosis, and therapy planning related to spines. Segmentation of spinal canal provides helpful references to parcellate other anatomical structures and contributes to the understandings of full-body scans essentially [1]. Given spinal canal, it is much easier to(More)
In this paper, we present a novel probabilistic framework for automatic follicle quantification in 3D ultrasound data. The proposed framework robustly estimates size and location of each individual follicle by fusing the information from both global and local context. Follicle candidates at detected locations are then segmented by a novel database guided(More)
The level of urinary creatinine in clinic diagnosis is one of the useful index of renal function, and is often used as a reference of some biochemical substance determined in random urine. In this paper, a rapid multiple-injection capillary electrophoresis(CE) method for the determination of urinary creatinine is reported. A 36 cm x 50 microns coated(More)
Pseudouridine, mainly as a degradation product of transfer ribonucleic acid, has been shown to be excreted in abnormal amounts in the urine of patients with cancer and can be used as one of the potentially valuable tumor markers. In this paper, a method for the rapid determination of human urinary pseudouridine by HPCE is reported. We used a 24 cm x 25(More)
Objective: To investigate the clinical significance of expression level of thyroid hormone receptor interactors 13 (TRIP13) gene to probe its function and downstream molecular mechanism in chronic lymphocytic leukemia (CLL) . Methods: Real-time quantitative PCR method was used to detect the expression levels of TRIP13 mRNA of CD19(+) B lymphocytes in 30(More)
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