Kevin S. Robinson

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BACKGROUND When ultrasonography is used to investigate deep-vein thrombosis, serial testing is recommended for those who test negative initially. Serial testing is inconvenient for patients and costly. We aimed to assess whether the calculation of pretest probability of deep-vein thrombosis, with a simple clinical model, could be used to improve the(More)
PURPOSE Bendamustine hydrochloride is an alkylating agent with novel mechanisms of action. This phase II multicenter study evaluated the efficacy and toxicity of bendamustine in patients with B-cell non-Hodgkin's lymphoma (NHL) refractory to rituximab. PATIENTS AND METHODS Patients received bendamustine 120 mg/m(2) intravenously on days 1 and 2 of each(More)
PURPOSE Bendamustine HCl is a bifunctional mechlorethamine derivative with clinical activity in the treatment of non-Hodgkin's lymphoma. This study evaluated bendamustine plus rituximab in 67 adults with relapsed, indolent B-cell or mantle cell lymphoma without documented resistance to prior rituximab. PATIENTS AND METHODS Patients received rituximab 375(More)
Designs for ÿtting a generalized linear model depend on the unknown parameters of the model. The use of any design optimality criterion would therefore require some prior knowledge of the parameters. In this article, a graphical technique is proposed for comparing and evaluating designs for a logistic regression model. Quantiles of the scaled mean-squared(More)
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