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The existence of a specialized mechanism supporting auditory motion processing in humans is a matter of debate in the psychophysical literature. Recent functional neuroimaging data appear to have resolved the debate in favor of a specialized motion system in that several studies have found cortical regions that seem to be motion selective. While all these(More)
Several lines of evidence show that posterior portions of left auditory cortex participate in aspects of speech production. A current hypothesis is that these regions play a specific role in processing phonological codes. We used event-related fMRI to test this hypothesis. Subjects covertly named objects that had names varying in length from one to four(More)
Although it is generally acknowledged that at least two processing streams exist in the primate cortical auditory system, the function of the posterior dorsal stream is a topic of much debate. Recent studies have reported selective activation to auditory spatial change in portions of the human planum temporale (PT) relative to nonspatial stimuli such as(More)
Thirteen-channel visual evoked potentials (VEPs) to pattern-onset were recorded with stimuli restricted to individual octants of the peripheral field, to halves and to quadrants of the fovea. The voltage of the CI component was measured in each channel to define its topography for each stimulated sector. The potential fields so obtained were then analysed(More)
Sebaceous glands are intriguing glands that are found throughout the human body except on the palms of the hands and soles of the feet. The true function of these glands has yet to be determined, but there are several theories, including antioxidant effects, antibacterial effects, and transport of pheromones. Sebaceous glands produce lipids that are(More)
The existence of a specialized human cortical area for the processing of auditory motion is still a matter of debate. Initial functional imaging studies identified the planum temporale as being motion selective. Recent data contrasting spatially varying stationary stimuli with moving stimuli found no difference in the amount of activation between the two(More)
Changes in the lungs due to smoking include inflammation, epithelial damage, and remodeling of the airways. Airway inflammation is likely to play a critical role in the genesis and progression of tobacco smoke-induced airway disease. Soluble epoxide hydrolase (sEH) is involved in the metabolism of endogenous chemical mediators that play an important role in(More)
Epidemiologic studies have shown that airborne particulate matter (PM) with a mass median aerodynamic diameter < 10 microm (PM10) is associated with an increase in respiratory-related disease. However, there is a growing consensus that particles < 2.5 microm (PM2.5), including many in the ultrafine (< 0.1 microm) size range, may elicit greater adverse(More)
A Ab bs st tr ra ac ct t The theoretical possibility of applying gene transfer methodologies to the human germline is explored. Transgenic methods for genetically manipulating embryos may in principle be applied to humans. In particular, microinjection of retroviral vector appears to hold the greatest promise, with transgenic primates already obtained from(More)
Although primary particle emissions of ash from coal-fired power plants are well controlled, coal fly ash (CFA) can still remain a significant fraction of the overall particle exposure for some plant workers and highly impacted communities. The effect of CFA on pulmonary and systemic inflammation and injury was measured in male Sprague-Dawley rats exposed(More)