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Fibroblasts are found in various proportions across the spectrum of carcinomas, constituting , in many cases, the preponderant cell population of the tumor stroma. Data from co-culture and reconstitution experiments indicate that fibroblasts have a prominent role in defining the rate and extent of cancer progression and metastasis. in a recent issue of Cell(More)
PURPOSE Although many patients with mycosis fungoides presenting with stage I disease enjoy an indolent disease course and normal life expectancy, about 15% to 20% of them progress to higher stages and most ultimately succumb to their disease. Currently, it is not possible to predict which patients will progress and which patients will have a stable(More)
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