Kevin P. McGrath

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Recombinant DNA methods were used to create artificial proteins that undergo reversible gelation in response to changes in pH or temperature. The proteins consist of terminal leucine zipper domains flanking a central, flexible, water-soluble polyelectrolyte segment. Formation of coiled-coil aggregates of the terminal domains in near-neutral aqueous(More)
Efficient catalytic reactions that can generate C-C bonds enantioselectively, and ones that can produce trisubstituted alkenes diastereoselectively, are central to research in organic chemistry. Transformations that accomplish these two tasks simultaneously are in high demand, particularly if the catalysts, substrates and reagents are inexpensive and if the(More)
INTRODUCTION The National Science Foundation and other agencies of the U.S. government have asked the World Technology (WTEC) Division of the International Technology Research Institute to perform an assessment of status and trends in tissue-engineering research and applications around the world in comparison to that in the United States. The purpose of(More)
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