Kevin L Taylor

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Increased plasminogen activator inhibitor 1 (PAI-1) has been linked to not only thrombosis and fibrosis but also to obesity and insulin resistance. Increased PAI-1 levels have been presumed to be consequent to obesity. We investigated the interrelationships of PAI-1, obesity, and insulin resistance in a high-fat/high-carbohydrate (HF) diet-induced obesity(More)
Interferons (IFNs) have proven antitumor activity against a variety of human malignancies, which may result, at least in part, from inhibition of angiogenesis. The objective of this study was to identify IFN-stimulated genes (ISGs) that played a role in mediation of angiogenic inhibition. IFN-beta was a more potent antiangiogenic agent compared to(More)
OBJECTIVE To evaluate the reports of resistance and cross-resistance to pediculicides in the head louse (Pediculus capitis), as well as the mechanisms involved. DATA SOURCES Literature identified through a MEDLINE search (1966-April 2000) and through other secondary literature databases and/or bibliographies of pertinent articles. DATA SYNTHESIS Head(More)
Interferon-alpha (IFN-alpha) has proved effective in the treatment of hemangiomas, hemangioblastomas, and Kaposi's sarcoma. To investigate the ability of IFNs to inhibit angiosarcoma, we used two transformed murine endothelial cell lines that form angiosarcomas in vivo. SVR and MS1-VEGF cell lines express oncogenic H-ras or vascular endothelial growth(More)
Sporadically missing data sources in syndromic surveillance systems result in inaccurate counts and detection algorithm results. We examined how data quality issues relating to missing data sources propagate through a surveillance system and devised a method to track and visualize the resulting data quality issues.
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