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Tolbutamide hydroxylation has been investigated in human liver microsomes. Anti-human liver NADPH-cytochrome P-450 reductase IgG inhibited hydroxytolbutamide formation and this metabolite was not(More)
OBJECTIVES To estimate the cost-effectiveness of screening for amblyopia and strabismus in children aged up to 4-5 years, also identifying the major areas of uncertainty and so inform future research(More)