Kevin H. Brown

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We report initial results of exposing low-Z solid and high-Z liquid targets to 150-ns, 4 × 10 12 proton pulses with spot sizes on the order of 1 to 2 mm. The energy depo-sition density approached 100 J/g. Diagnostics included fiberoptic strain sensors on the solid target and high-speed photography of the liquid targets. This work is part of the R&D program(More)
Cdc42, activated with GTPgammaS, induces actin polymerization in supernatants of lysed neutrophils. This polymerization, like that induced by agonists, requires elongation at filament barbed ends. To determine if creation of free barbed ends was sufficient to induce actin polymerization, free barbed ends in the form of spectrin-actin seeds or sheared(More)
Transient solid dynamics simulations are among the most widely used engineering calculations. Industrial applications include vehicle crashworthiness studies, metal forging, and powder compaction prior to sintering. These calculations are also critical to defense applications including safety studies and weapons simulations. The practical importance of(More)
Cold seep ecosystems can support enormous biomasses of free-living and symbiotic chemoautotrophic organisms that get their energy from the oxidation of methane or sulfide. Most of this biomass derives from animals that are associated with bacterial symbionts, which are able to metabolize the chemical resources provided by the seeping fluids. Often these(More)
PURPOSE Evaluation of a new software tool for generation of simulated low-dose computed tomography (CT) images from an original higher dose scan. MATERIALS AND METHODS Original CT scan data (100 mAs, 80 mAs, 60 mAs, 40 mAs, 20 mAs, 10 mAs; 100 kV) of a swine were acquired (approved by the regional governmental commission for animal protection).(More)
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