Kevin F. Kennedy

Learn More
BACKGROUND Benefits of drug-eluting stents (DES) in percutaneous coronary intervention (PCI) are greatest in those at the highest risk of target-vessel revascularization (TVR). Drug-eluting stents cost more than bare-metal stents (BMS) and necessitate prolonged dual antiplatelet therapy (DAPT), which increases costs, bleeding risk, and risk of complications(More)
CONTEXT Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown. OBJECTIVE To assess the appropriateness of PCI in the United States. DESIGN, SETTING, AND PATIENTS Multicenter, prospective study of patients within the National Cardiovascular Data Registry(More)
BACKGROUND We developed risk models for predicting acute kidney injury (AKI) and AKI requiring dialysis (AKI‐D) after percutaneous coronary intervention (PCI) to support quality assessment and the use of preventative strategies. METHODS AND RESULTS AKI was defined as an absolute increase of ≥0.3 mg/dL or a relative increase of 50% in serum creatinine(More)
BACKGROUND Rehospitalizations for acute coronary syndromes (ACS) and coronary revascularization after an acute myocardial infarction (AMI) are not only common and costly but can also impact patients' quality of life. In contrast to mortality and all-cause readmissions, little insight is available into risk factors associated with ACS and revascularization(More)
Risk prediction is an important field in applied statistics. For example, in clinical research, predicting the development of adverse medical conditions is the object of many studies. However, this concept is multidisciplinary. Many published models exist to predict dichotomous outcomes, ranging widely from a model to predict winners in the NCAA basketball(More)
BACKGROUND The volume-outcome relationship associated with intensive care unit (ICU) experience with managing acute myocardial infarction (AMI) remains inadequately understood. METHODS AND RESULTS Within a multicenter clinical ICU database, we identified patients with a primary ICU admission diagnosis of AMI between 2008 and 2010 to evaluate whether(More)
BACKGROUND Contemporary rates of oral anticoagulant (OAC) therapy and associated outcomes among patients undergoing percutaneous coronary intervention (PCI) have been poorly described. METHODS AND RESULTS Using data from an integrated health care system from 2009 to 2014, we identified patients on OACs within 30 days of PCI. Outcomes included in-hospital(More)
BACKGROUND Rehospitalizations following acute myocardial infarction for unplanned coronary revascularization and unstable angina (UA) are often included as parts of composite end points in clinical trials. Although clearly costly, the clinical relevance of these individual components has not been described. METHODS AND RESULTS Patients enrolled in a(More)
BACKGROUND The Centers for Medicaid and Medicare Services (CMS) and the National Cardiovascular Data Registry (NCDR) track primary percutaneous coronary intervention (PCI) performance in the form of door-to-balloon time. For quality assessment, exceptions are made for patients with "unavoidable delays" in both registries, yet it remains unclear how(More)
BACKGROUND Early readmission after PCI is an important contributor to healthcare expenditures and a target for performance measurement. The extent to which 30-day readmissions after PCI are preventable is unknown yet essential to minimizing their occurrence. METHODS AND RESULTS PCI patients readmitted to hospital at which PCI was performed within 30 days(More)