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OBJECTIVE The purpose of this study was to establish whether a correlation exists between the CT pulmonary angiographic clot burden score, the ECG score at diagnosis, and the 12-month mortality rate among patients diagnosed with pulmonary embolism. SUBJECTS AND METHODS A total of 523 consecutive patients who underwent CT pulmonary angiography for a(More)
Serum samples from ten endogamous populations of Assam, India-Brahmins, Kalitas, Kaibartas, Muslims, Ahoms, Karbis, Kacharis, Sonowals, Chutiyas, and Rajbanshis-were typed for G1m (1, 2, 3, 17), G3m (5, 10, 11, 13, 14, 15, 16, 21, 26), and Km (1). Among Brahmins, Kalitas, Kaibartas, Muslims, Ahoms, Sonowals, Chutiyas, and Rajbanshis, five different Gm(More)
The enantioselective synthesis of substituted pyrrolidines through a mild Lewis-acid catalyzed three-component coupling reaction between picolinaldehyde, amino acids, and activated olefins is reported. The reaction uses low catalyst loadings of commercially available chiral diamines and copper triflate proposed to self-assemble in conjunction with the(More)
The vast increase of pertinent information available to drug discovery scientists means that there is a strong demand for tools and techniques for organizing and intelligently mining this information for manageable human consumption. At Indiana University, we have developed an infrastructure of chemoinformatics Web services that simplifies the access to(More)
In recent years, there has been an explosion in the availability of publicly accessible chemical information, including chemical structures of small molecules, structure-derived properties and associated biological activities in a variety of assays. These data sources present us with a significant opportunity to develop and apply computational tools to(More)
The changes of the secondary sex ratio in Bremen (North Germany) from 1826 up to 1978 are compared with those of Germany in the period from 1872 to 1978. To some extent there are marked differences. The oscillation of the secondary sex ratio in Bremen is more extended in Germany. On the average in Bremen the values are lower in the 19th century than in the(More)
The vast increase of pertinent information available to drug discovery scientists means that there is strong demand for tools and techniques for organizing and intelligently mining this information for manageable human consumption. At Indiana University, we are developing techniques for " smart mining " of this information, based on web services, workflows,(More)
Ten different population groups of Assam - Brahmins, Kalitas, Kaibartas, Rajbanshis, Muslims, Ahoms, Chutias, Kacharis, Karbis and Sandwals - have been typed for haptoglobin and for transferrin (Tf) and Gc subtype polymorphisms. Tf and Gc allele subtype frequencies show a considerable inter-population heterogeneity. From genetic distance analysis it appears(More)
The question, whether the seasonal variation of the birth frequencies are changing with the increase of birthcontrol practice in the population is subject of the present study. The changes of the relevant demographic parameters in this context are discussed first. The study is based on the official monthly records of live- and stillbirths from 1826 to 1979(More)