Kevin E. Finucane

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Progressive threshold loading (PTL) is frequently used to assess inspiratory muscle endurance in health and disease. We and others have noted a systematic increase in endurance with the first few exposures to the task in subjects previously naïve to PTL, which may not be related to conditioning of the muscles themselves. The purpose of this study was to(More)
Diaphragm activation can be quantified by measuring the root mean square of crural EMG (RMSdi) (Beck J, Sinderby C, Lindstrom L, and Grassino A, J Appl Physiol 85: 1123-1134, 1998). To examine intersubject and day-to-day variation in the RMSdi-Pco(2) relationship, end-tidal Pco(2), minute ventilation (Ve), respiratory frequency (f(B)), and RMSdi were(More)
A semi-automatic method is described for tracking the contour of the diaphragm in lateral X-ray image sequences. It is part of a method being developed to quantify diaphragm function non-invasively. Initialization is achieved by interactive segmentation of the diaphragm contour and identification of landmarks. The method relies on modelling the contour(More)
To quantify any mechanical inhibitory effect of nasal intermittent positive pressure ventilation (IPPV) on inspiratory activity of the diaphragm we ventilated five conscious relaxed subjects on two occasions at respiratory rates similar to quiet breathing (QB) and at three levels of applied pressure (Pappl)--6, 9 and 12 cmH2O, each during hypocapnia (P(CO2)(More)
Transcutaneous bilateral phrenic nerve stimulation (tPNS) is frequently used to assess diaphragmatic function in humans. Commonly, stimulation is performed with hand-held electrodes; however, these are unsuitable for studies requiring repeated PNS and where recruitment of rib cage and neck muscles may shift the probes in relation to the nerves. In this(More)
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