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  • Kevin D. Burris, Thaddeus F. Molski, +5 authors Perry B. Molinoff
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2002 (First Publication: 1 July 2002)
  • Aripiprazole is the first next-generation atypical antipsychotic with a mechanism of action that differs from currently marketed typical and atypical antipsychotics. Aripiprazole displays propertiesContinue Reading
  • Yoshihiro Tadori, Takashi Miwa, +4 authors Tetsuro Kikuchi
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2005 (First Publication: 1 May 2005)
  • Aripiprazole is the first clinically approved atypical antipsychotic agent having dopamine D2 receptor partial agonist activities. To evaluate aripiprazole's agonist and antagonist properties, weContinue Reading
  • Arlene D. Stark, Shaun Jordan, +8 authors Kevin D. Burris
  • Psychology, Medicine
  • Psychopharmacology
  • 2006 (First Publication: 1 February 2007)
  • BackgroundAripiprazole (7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy}-3,4-dihydro-2(1H)-quinolinone) is a novel antipsychotic with a mechanism of action that differs from current typical andContinue Reading
  • Elaine sanders-Bush, Kevin D. Burris, K M Knoth
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1988 (First Publication: 1 September 1988)
  • Based on electrophysiological, radioligand binding, and behavioral studies in laboratory animals, it is generally believed that the psychotomimetic effects of the phenethylamine and indolealkylamineContinue Reading
  • Tarsis F Brust, Michael P Hayes, David L Roman, Kevin D. Burris, Val J. Watts
  • Medicine, Chemistry
  • The Journal of Pharmacology and Experimental…
  • 2015 (First Publication: 1 March 2015)
  • G protein–coupled receptors (GPCRs) often activate multiple signaling pathways, and ligands may evoke functional responses through individual pathways. These unique responses provide opportunitiesContinue Reading
  • Kevin D. Burris, Marsha Breeding, Elaine sanders-Bush
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1991 (First Publication: 1 September 1991)
  • Activation of central serotonin 5HT2 receptors is believed to be the primary mechanism whereby lysergic acid diethylamide (LSD) and other hallucinogens induce psychoactive effects. This hypothesis isContinue Reading