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OBJECTIVE To measure the levels and patterns of physical activity, using accelerometers, of 11-year-old children participating in the Avon Longitudinal Study of Parents and Children (ALSPAC). DESIGN Cross-sectional analysis. SETTING ALSPAC is a birth cohort study located in the former county of Avon, in the southwest of England. This study used data(More)
BACKGROUND Objective methods can improve accuracy of physical activity measurement in field studies but uncertainties remain about their use. METHODS Children age 11 years from the Avon Longitudinal Study of Parents and Children (ALSPAC), were asked to wear a uni-axial accelerometer (MTI Actigraph) for 7 days. RESULTS Of 7159 children who attended for(More)
OBJECTIVE To investigate associations between physical activity at age 12 and subsequent adiposity at age 14. DESIGN Prospective birth cohort study with data collected between 2003 and 2007. SETTING Original recruitment in 1991-2 of 14,541 pregnant women living in the former County of Avon (United Kingdom). PARTICIPANTS At age 12, 11,952 children were(More)
OBJECTIVE Epidemiological studies have shown an association between OA and increased BMD. To explore the nature of this relationship, we examined whether the risk of OA is increased in individuals with high bone mass (HBM), in whom BMD is assumed to be elevated due to a primary genetic cause. METHODS A total of 335,115 DXA scans were screened to identify(More)
PURPOSE Time spent in "sports/outdoor activity" has shown a negative association with incident myopia during childhood. We investigated the association of incident myopia with time spent outdoors and physical activity separately. METHODS Participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) were assessed by noncycloplegic(More)
Obesity is a risk factor for fibromyalgia in adults, but whether a similar relationship exists in children is uncertain. This study examined whether obesity is associated with reporting of musculoskeletal pain, including chronic regional pain (CRP) and chronic widespread pain (CWP), in adolescents, in a population-based setting. A pain questionnaire was(More)
Whether a certain level of impact needs to be exceeded for physical activity (PA) to benefit bone accrual is currently unclear. To examine this question, we performed a cross-sectional analysis between PA and hip BMD in 724 adolescents (292 boys, mean 17.7 years) from the Avon Longitudinal Study of Parents and Children (ALSPAC), partitioning outputs from a(More)
OBJECTIVE Although diagnostic criteria for generalized ligamentous laxity (hypermobility) in children are widely used, their validity may be limited, due to the lack of robust descriptive epidemiologic data on this condition. The present study was undertaken to describe the point prevalence and pattern of hypermobility in 14-year-old children from a(More)
We hypothesized that bone resorption acts to increase bone strength through stimulation of periosteal expansion. Hence, we examined whether bone resorption, as reflected by serum β-C-telopeptides of type I collagen (CTX), is positively associated with periosteal circumference (PC), in contrast to inverse associations with parameters related to bone(More)
BACKGROUND Objective measures of physical activity calibrated against energy expenditure may have limited utility in studying relationships with musculoskeletal phenotypes. We wished to assess an alternative approach using an accelerometer calibrated according to impact loading. METHODS Of the 17-year olds from the Avon Longitudinal Study of Parents and(More)