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Summary The safe use of inorganic nanoparticles (NPs) in biomedical applications remains an unresolved issue. The present review presents an overview of the cytotoxic effects of commonly usedExpand
  • Kevin Braeckmans, Liesbeth Peeters, Niek N. Sanders, Stefaan C De Smedt, J. DeMeester
  • Chemistry, Medicine
  • Biophysical journal
  • 2003 (First Publication: 1 October 2003)
  • Confocal scanning laser microscopes (CSLMs) are equipped with the feature to photobleach user-defined regions. This makes them a handy tool to perform fluorescence recovery after photobleachingExpand
  • Héloïse Ragelle, Raphael Riva, +9 authors Véronique Préat
  • Medicine, Chemistry
  • Journal of controlled release : official journal…
  • 2014 (First Publication: 28 February 2014)
  • This study aims at developing chitosan-based nanoparticles suitable for an intravenous administration of small interfering RNA (siRNA) able to achieve (i) high gene silencing without cytotoxicity andExpand
  • Ana Cristina Norberto Oliveira, Thomas Frans Martens, +6 authors Maria Elisabete Cunha Dias Real Oliveira
  • Medicine, Materials Science
  • ACS applied materials & interfaces
  • 2014 (First Publication: 18 April 2014)
  • This study describes a novel liposomal formulation for siRNA delivery, based on the mixture of the neutral lipid monoolein (MO) and cationic lipids of the dioctadecyldimethylammonium (DODA) family.Expand
  • Sander A. A. Kooijmans, Stephan Stremersch, +6 authors Pieter Vader
  • Medicine, Chemistry
  • Journal of controlled release : official journal…
  • 2013 (First Publication: 28 November 2013)
  • Extracellular vesicles (EVs) are specialised endogenous carriers of proteins and nucleic acids and are involved in intercellular communication. EVs are therefore proposed as candidate drug deliveryExpand
  • Katrien Forier, Koen van Raemdonck, Stefaan C De Smedt, Jo Demeester, Tom Coenye, Kevin Braeckmans
  • Chemistry, Medicine
  • Journal of controlled release : official journal…
  • 2014 (First Publication: 28 September 2014)
  • Biofilms are matrix-enclosed communities of bacteria that show increased antibiotic resistance and the capability to evade the immune system. They can cause recalcitrant infections which cannot beExpand
  • Freya Joris, Bella B. Manshian, Karen Peynshaert, Stefaan C. De Smedt, Kevin Braeckmans, Stefaan J. Soenen
  • Chemistry, Medicine
  • Chemical Society reviews
  • 2013 (First Publication: 7 October 2013)
  • The number of newly engineered nanomaterials is vastly increasing along with their applications. Despite the fact that there is a lot of interest and effort is being put into the development ofExpand