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  • Clinton G L Veale, Roya Zoraghi, +6 authors Michael T. Davies‐Coleman
  • Biology, Medicine
  • Journal of natural products
  • 2015 (First Publication: 27 March 2015)
  • As part of an ongoing study to elucidate the SAR of bisindole alkaloid inhibitors against the evolutionary conserved MRSA pyruvate kinase (PK), we present here the synthesis and biological activityContinue Reading
  • Farha Naz, Faez Iqbal Khan, +8 authors Md. Imtaiyaz Hassan
  • Medicine, Chemistry
  • International journal of biological…
  • 2018 (First Publication: 1 February 2018)
  • Microtubule affinity regulating kinase 4 (MARK4) is a member of AMP-activated protein kinase, found to be involved in apoptosis, inflammation and many other regulatory pathways. Since, its aberrantContinue Reading
  • Taj Mohammad, Faez Iqbal Khan, Kevin A. Lobb, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan
  • Medicine, Chemistry
  • Journal of biomolecular structure & dynamics
  • 2019 (First Publication: 1 April 2019)
  • Microtubule affinity-regulating kinase 4 (MARK4) has recently been identified as a potential drug target for several complex diseases including cancer, diabetes and neurodegenerative disorders.Continue Reading
  • Thommas Mutemi Musyoka, Aquillah M. Kanzi, Kevin A. Lobb, Özlem Tastan Bishop
  • Biology, Medicine
  • Scientific reports
  • 2016 (First Publication: 31 March 2016)
  • Identification of potential drug targets as well as development of novel antimalarial chemotherapies with unique mode of actions due to drug resistance by Plasmodium parasites are inevitable.Continue Reading
  • Anam Beg, Faez Iqbal Khan, Kevin A. Lobb, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan
  • Medicine, Chemistry
  • Journal of biomolecular structure & dynamics
  • 2019 (First Publication: 1 May 2019)
  • Abstract Calcium/calmodulin-dependent protein kinase IV (CAMKIV) is associated with many diseases including cancer and neurodegenerative disorders and thus being considered as a potential drugContinue Reading
  • Shagufta H. Khan, Faez Iqbal Khan, +6 authors Md Imtaiyaz Hassan
  • Chemistry, Medicine
  • International journal of biological…
  • 2018 (First Publication: 1 May 2018)
  • Mammalian cell entry protein (Mce4A) is a member of MCE-family, and is being considered as a potential drug target of Mycobacterium tuberculosis infection because it is required for invasion andContinue Reading
  • Sunayana Begum Syed, Faez Iqbal Khan, +6 authors Faizan Ahmad
  • Chemistry, Medicine
  • International journal of biological…
  • 2018 (First Publication: 1 October 2018)
  • Integrin-linked kinase (ILK) is a ubiquitously expressed Ser/Thr kinase which plays significant role in the cell-matrix interactions and growth factor signalling. In this study, guanidinium chlorideContinue Reading