Ketheesan Thirusittampalam

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The aim of this paper is to detail the development of a novel tracking framework that is able to extract the cell motility indicators and to determine the cellular division (mitosis) events in large time-lapse phase-contrast image sequences. To address the challenges induced by nonstructured (random) motion, cellular agglomeration, and cellular mitosis, the(More)
The quantitative analysis of live cells is a key issue in evaluating biological processes. The current clinical practice involves the application of a tedious and time consuming manual tracking procedure on large amount of data. As a result, automatic tracking systems are currently developed and evaluated. However, problems caused by cellular division,(More)
The quantitative analysis of cellular migration has found many clinical applications as it can be used in the study of a large spectrum of biological processes such as tumor development and wound healing. These studies are commonly conducted on datasets that consists of a large number of time lapse images, a fact that rendered the application of human(More)
With the proliferation of modern microscopy imaging technologies the amount of data that has to be analysed by biologists is constantly increasing and as a result the development of automatic approaches that are able to track cellular structures in timelapse images has become an important field of research. The aim of this paper is to detail the development(More)
Cell migration and cell division are two key processes that are associated with a wide range of biological phenomena including embryogenesis, inflammation, wound healing, tumour development etc. The study of these cellular processes has received a substantial interest from the cell and molecular scientists since the understanding of the mechanisms that(More)
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