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  • Hans-Joachim Lueck, Andreas du Bois, +15 authors Gunter von Minckwitz
  • Medicine
  • Breast Cancer Research and Treatment
  • 2013 (First Published: 1 June 2013)
  • Capecitabine/taxane combinations are highly active in metastatic breast cancer (MBC). We conducted a randomized, phase III, noninferiority trial comparing capecitabine plus paclitaxel (XP) withContinue Reading
  • Andreas du Bois, Jalid Sehouli, +21 authors Justine Rochon
  • Medicine
  • 2005 (First Published: 1 November 2005)
  • Paclitaxel-carboplatin-gemcitabine (TCG) as first-line treatment of ovarian cancer: a prospective multicenter phase II study (AGO-OVAR 8) followed by a prospectively randomized phase III GCIGContinue Reading
  • Werner Meier, Andreas Du Bois, +14 authors Jalid Sehouli
  • Medicine
  • Gynecologic oncology
  • 2012 (First Published: 1 August 2012)
  • OBJECTIVES This study evaluates whether a molecular targeted therapy with the farnesyltransferase inhibitor lonafarnib added to standard chemotherapy in first-line treatment of advanced ovarianContinue Reading
  • Pauline Wimberger, Hagen Sjard Bachmann, +11 authors Werner P. Meier
  • Medicine
  • 2014 (First Published: 20 May 2014)
  • e16534 Background: Despite promising preclinical findings regarding clinical utility of farnesyltransferase inhibitors (FTI), such as lonafarnib, success of clinical studies is limited. In someContinue Reading