Kerstin Helfrich

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Matrix metalloproteinases (MMPs) are a large family of Zn2+ endopeptidases that are expressed in inflammatory conditions and are capable of degrading connective tissue macromolecules. MMP-like enzymes are also involved in the processing of a variety of cell surface molecules including the pro-inflammatory cytokine TNF-alpha. MMPs and TNF-alpha have both(More)
BACKGROUND Since the early 1990s more than 1,800 patients with lesions suspicious for Buruli ulcer disease (BUD) have been reported from Togo. However, less than five percent of these were laboratory confirmed. Since 2007, the Togolese National Buruli Ulcer Control Program has been supported by the German Leprosy and Tuberculosis Relief Association (DAHW).(More)
BACKGROUND In a previous study PCR analysis of clinical samples from suspected cases of Buruli ulcer disease (BUD) from Togo and external quality assurance (EQA) for local microscopy were conducted at an external reference laboratory in Germany. The relatively poor performance of local microscopy as well as effort and time associated with shipment of PCR(More)
Diese Dissertation ist auf dem Hochschulschriftenserver der ULB Bonn unter Abstract Few-body effects play an important role for the understanding of ultracold quantum gases. We make use of an effective field theory approach to investigate various aspects of universal few-body physics close to a Feshbach resonance. That is the regime where the scattering(More)
PURPOSE We report two experiments that address the role of stereopsis in viewing the fundus. METHODS Thirteen observers viewed stereo slides obtained by lateral displacement of a fundus camera. We quantified the capacity of seven clinicians (normal stereopsis) to resolve depth in a model eye viewed monocularly and binocularly. We also compared the ability(More)
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