Kerstin Eberhardt

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Nuclear magnetic resonance spectroscopy (1H-MRS) is a non-invasive method in detecting abnormal spectra of various brain metabolites containing N-acetylaspartate (NAA), Choline (Cho), Creatine (Cr), gamma-Aminobutyric acid (GABA) and Glutamate. Technical processing of the MR-systems, improved automated shimming methods and further development of special(More)
BACKGROUND Ictal fear (IF) is most frequently associated with epileptic discharges from mesial temporal areas. OBJECTIVES To determine whether patients with IF were more likely to become seizure free after anteromesial temporal lobe resection compared with those without IF and whether they show more anteriorly pronounced metabolic changes assessed by(More)
PURPOSE Hippocampal neuron loss and associated memory deficits are characteristic of intractable temporal lobe epilepsy (TLE). Proton chemical shift imaging (CSI) spectroscopy is a sensitive tool for detecting neuronal loss. The aim of this study was to investigate the correlation between memory functions and results provided by CSI spectroscopy of the(More)
OBJECTIVE To investigate development of radiographic damage in hands and feet of patients with early rheumatoid arthritis (RA) monitored prospectively for 10 years, and to search for prognostic factors. PATIENTS AND METHODS 181 patients with early RA (mean disease duration one year) were assessed annually with radiographs of hands and feet during years(More)
The spatial understanding of vascular information obtained with CT and MR is tremendously assisted by direct volume rendering since it provides semi-transparent views of the entire data giving insight to hidden structures. Ensuring a convenient diagnosis of complex vessel topol-ogy, we propose an approach based on 3D texture mapping which ensures(More)
The increasing capabilities of magnetic resonance (MR) imaging and multisection spiral computed tomography (CT) to acquire volumetric data with near-isotropic voxels make three-dimensional (3D) postprocessing a necessity, especially in studies of complex structures like intracranial vessels. Since most modern CT and MR imagers provide limited postprocessing(More)
OBJECTIVES To evaluate costs, benefits, and cost effectiveness of tumour necrosis factor inhibitor treatment over one year in routine clinical practice. MATERIALS AND METHODS At four rheumatology units in southern Sweden treatment of 160 consecutive patients with RA was started with either etanercept or infliximab. The economic analysis was based on 116(More)
Conventional myelography was compared with a new type of MR technique using a fat-suppressing 3D fast imaging with steady precession (FISP) sequence for diagnosis of the lumbar root compression syndrome. 80 patients with discogenic disease in the lumbar spine were examined with a 1.0-T whole-body MR system (Siemens Magnetom Impact, Erlangen, Germany). A(More)
OBJECTIVE When treatments with the potential to change the natural history of a disease are introduced, their longer-term effect on costs and quality of life (utility) has to be estimated using economic models. However, to remain useful tools, models must be updated when new information becomes available. Our earlier models in rheumatoid arthritis (RA) have(More)