Most investigators have found a decrease in emotional defecation in rats given neuroleptics in novel environments, supporting their action as a major tranquilizer. We have found, however, that in rats a profound increase in emotional defecation can result from neuroleptic administration in well habituated environments, such as the homecage. Anticholinergics… (More)
The neuroleptic haloperidol was found to produce increased defecation in laboratory rats when tested in well habituated environments. It is well known that haloperidol induces catalepsy through antagonism of striatal dopaminergic receptor mechanisms. When another cataleptic agent, morphine, was tested, no significant increases in defectation were detected.… (More)
The increased locomotor activity induced by systemic injections of d-amphetamine or scopolamine in rats was studied in Digiscan Animal Activity Monitors. This multifactorial analysis of locomotion demonstrated that activity measures of horizontal (ambulatory), vertical (rearing), stereotypic, and rotational behaviors differed depending on dose and drug. The… (More)
AIM To identify which factors influence the final visual acuity in children with anisometropic amblyopia. METHODS A retrospective analysis of 112 children with anisometropic amblyopia, identified from examining all case notes of children who had failed preschool or school screening. RESULTS The age at presentation had no effect on the final visual… (More)
Recently, Bauer reported that amphetamine did not increase rearing behavior in adult rats. This result is at variance with many earlier reports demonstrating that amphetamine does increase rearing behavior. Because Bauer's automated measure only detected rearing when it occurred on the wall of the cage, it is possible that amphetamine only increased rearing… (More)
Background: This study aimed to determine epidemiology and outcome for patients presenting to emergency departments (ED) with shortness of breath who were transported by ambulance.
Background: Dual infection with HIV-1 and HIV-2, which is not uncommon in West Africa, has important implications for transmission , progression, and antiretroviral therapy. Few studies have examined HIV viral dynamics in this setting. Methods: We compared HIV-1 and HIV-2 viral loads from 65 dually infected, antiretroviral therapy-naı¨ve Senegalese… (More)
Aim: To identify which factors influence the final visual acuity in children with anisometropic amblyo-pia. Methods: A retrospective analysis of 112 children with anisometropic amblyopia, identified from examining all case notes of children who had failed preschool or school screening. Results: The age at presentation had no effect on the final visual… (More)