Kerim Çayır

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PURPOSE The aim of the study was to investigate the association between the molecular subtypes and patterns of relapse in breast cancer patients who had undergone curative surgery. METHODS We retrospectively evaluated 1,350 breast cancer patients with relapses after curative surgery between 1998 and 2012 from referral centers in Turkey. Patients were(More)
Cisplatin (CDDP), one of the most active cytotoxic agents against cancer, has adverse side effects, such as nephrotoxicity and hepatotoxicity. The present study was designed to investigate the potential protective effect of pomegranate seed extract (PSE) against oxidative stress caused by CDDP injury of the kidneys and liver by measuring tissue biochemical(More)
Aim: Upper gastrointestinal tract carcinomas are major health problem around the world. Esophageal cancer (EC) is usually diagnosed at an advanced stage; therefore most therapeutic approaches are palliative. The aim of the study was to investigate the possible relationship between serum activities of paraoxonase (PON1) and arylesterase (ARE), and(More)
Aim: This study was performed to determine the levels of depression and anxiety, and coping strategies, and the effects of the levels of depression and anxiety on strategies for coping with stress in cancer patients. Method: The study was designed as a definitive and correlation searching investigation and has been performed at the Medical Oncology Clinic(More)
Sarcoidosis is a multisystem disease of unknown etiology characterized by the formation of noncaseating granulomas in the affected organs. Although different series report variable incidences of skin involvement during the course of the disease, nearly one-fourth of sarcoidosis patients have skin involvement (1). Lupus pernio (LP) was first described by(More)
Pityriasis rosea is a short-lived rash that commences initially as a large so-called ‘herald’ patch followed by a rapidly evolving eruption on the trunk and extremities. Characteristic pattern of lesions follow the lines of cleavage in a ‘christmas tree’ distribution. PR is most frequently seen between first and third decade but a range of 3 month to 83(More)
OBJECTIVE Gastric cancer is an important disease that is seen all over the world and that threats public health. At the same time, gastric cancer is a heterogeneous disorder with multifactorial etiologies. Recent studies have shown a significant association between HLA antigens and gastric adenocarcinoma. The aim of the present study was to determine the(More)
BACKGROUND/AIMS In the present study, the frequency of ErbB-2 overexpression and its relationship with pathologic parameters on patients with gastric cancer in Eastern Anatolia of Turkey was studied. MATERIALS AND METHODS A total of 32 newly diagnosed patients were enrolled in the study. DNA isolation was performed on paraffinized tumor tissues obtained(More)
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