Kenzo Sakai

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  • Kenzo Sakai
  • The Japanese journal of experimental medicine
  • 1975
The time-dependent distribution of 203Hg-methylmercuric chloride has been studied in the tissue cells of rats by means of microautoradiographic examination and in the liver cells by means of electron autoradiography. Furthermore, the radioactivity of 203Hg in the various organs was measured at the same time. A possible way was suggested to prove that(More)
The catecholaminergic neurons of senescence-accelerated mice (SAM-P8) were analyzed by immunohistochemical microphotometry in terms of immunoreactivities to aromatic L-amino acid decarboxylase (AADC), dopamine (DA), or noradrenaline (NA). Accelerated senescence-resistant mice (SAM-R1) were used as control mice. The immunoreactivities to AADC, DA, and NA of(More)
1. The mode of action of histamine was investigated on the rat isolated small intestine perfused at a fixed flow rate through the superior mesenteric artery with blood from the carotid artery of a heparinized donor rat. Compounds were closely injected into the superior mesenteric artery. 2. Increasing doses (1 to 100 micrograms) of histamine caused a(More)
1 Experiments were carried out on rat isolated heart preparations in which the coronary vasculature was perfused through the aorta at a constant flow rate with arterial blood from donor animals. Single doses of drugs were injected into the aortic cannula. 2 Small doses of acetylcholine, carbachol or bethanechol decreased perfusion pressure (PP) without(More)
In this study, cholesterin was implanted in the subcutaneous tissue in mice to induce the formation of cholesterol granuloma. Histological examination was carried out to determine the type and source of cells. The tissue surrounding the embedded cholesterin was examined histologically within the period of 6 months. Cell differentiation in cholesterol(More)