Kenta Korematsu

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We have cloned full-length cDNA of a novel mouse cadherin ("mCad8"). The deduced amino acid sequence of the mature form of mCad8 shows 98.2% identity with the sequence of human cadherin-8. The expression of mCad8 was studied by in situ hybridization in mouse embryos of 9.5-14 days gestation (E9.5-E14). Results show that mCad8 expression is restricted to(More)
The expression of cadherin-8 was mapped by in situ hybridization in the embryonic and postnatal mouse central nervous system (CNS). From embryonic day 18 (E18) to postnatal day 6 (P6), cadherin-8 expression is restricted to a subset of developing brain nuclei and cortical areas in all major subdivisions of the CNS. The anlagen of some of the(More)
Stress signals cause abnormal proteins to accumulate in the endoplasmic reticulum (ER). Such stress is known as ER stress, which has been suggested to be involved in neurodegenerative diseases, diabetes, obesity and cancer. ER stress activates the unfolded protein response (UPR) to reduce levels of abnormal proteins by inducing the production of chaperon(More)
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