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The University of Iowa's Psychiatric Iowa Neuroimaging Consortium (PINC) has developed a program for mutual information registration of BRAINS2 [2] data using ITK [1] classes, called BRAINSFit. We have written a helper class, itk::MultiModal3DMutualRegistrationHelper to simplify implementation and testing of different transform representations and(More)
OBJECTIVES To develop a practical, readily applied algorithm for primary health care providers to identify, evaluate, and manage constipation in children with autism spectrum disorders (ASDs). METHODS The Gastroenterology Committee of the Autism Speaks Autism Treatment Network (ATN), a multisite consortium of centers dedicated to improving standards of(More)
RATIONALE The role of purinergic signaling in human ENS is not well understood. We sought to further characterize the neuropharmacology of purinergic receptors in human ENS and test the hypothesis that endogenous purines are critical regulators of neurotransmission. EXPERIMENTAL APPROACH LSCM-Fluo-4/(Ca(2+))-imaging of postsynaptic Ca(2+) transients(More)
DISCLAMER This report was prepared by the Economic Modeling Working Group of the Generation IV International Forum (GIF). Neither GIF nor any of its members, nor any GIF member's national government agency or employee thereof, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness or(More)
The goal of this research is to determine whether Raman spectroscopy (RS), an optical method that probes the vibrational modes of tissue components, can be used in vivo to study changes in the mouse cervix during pregnancy. If successful, such a tool could be used to detect cervical changes due to pregnancy, both normal and abnormal, in animal models and(More)
Post-implementation analysis on Enterprise Resource Planning (ERP) systems has drawn attention to many structural shortcomings. Yet, no framework exists to compare the different structural features of the ERP system. This paper develops a framework to compare different enterprise-wide systems at the conceptual design level using size, coupling and(More)
UNLABELLED This study prospectively assessed whether positive screening surveys for autism spectrum disorders (ASDs) in children with functional defecation disorders (FDDs) accurately identify ASD. Parents of children (4-12 years) who met Rome III criteria for functional constipation (FC), FC with fecal incontinence (FI) and functional nonretentive FI(More)
At present time most system engineers do not have access to cognitive work analysis knowledge or training in terms that they could understand and apply in the system design process. This may lead to specifying systems requirements that do not account for cognitive strengths and limitations of the prospective users. This paper proposes integration of(More)
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