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The prophenoloxidase (proPO) activation pathway, like the vertebrate complement system, consists of a protease cascade and functions as a non-self-recognition system in these animals. Determining the molecular mechanism by which pattern recognition molecules differentiate non-self from self and transduce signals that stimulate defense responses is a key for(More)
The molecular mechanism of cellular immunity in arthropods has until recently been largely unknown, but with the development of a technique to isolate and handle the different blood cell types of crustaceans and with the purification of several proteins associated with the so-called proPO system of freshwater crayfish the processes have now begun to be(More)
We have adapted the primed in situ labelling (PRINS) protocol for gene mapping in polytene chromosomes of two dipteran species. The method was used to localize the genes for the Balbiani ring (BR) 2.1 and the iron-regulatory protein 1A (IRP1A) in polytene salivary gland chromosomes of Chironomus tentans, and Drosophila melanogaster respectively. Two(More)
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