Kenneth S. Miller

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In this expository article we survey some properties of completely monotonic functions and give various examples, including some famous special functions. Such function are useful, for example, in probability theory. It is known, [3], p.450, for example, that a function w is the Laplace transform of an infinitely divisible probability distribution on (0,∞),(More)
Inhibition of phosphodiesterase 10A (PDE10A) promotes cyclic nucleotide signaling, increases striatal activation, and decreases behavioral activity. Enhanced cyclic nucleotide signaling is a well established route to producing changes in gene expression. We hypothesized that chronic suppression of PDE10A activity would have significant effects on gene(More)
A study was conducted to investigate the effects of acute alcohol administration on affective states and verbal behavior during the ascending and descending limbs of the blood alcohol curve. Sixteen male social drinkers were given alcohol (1.0 g/kg) or placebo in a double-blind crossover research design. Subjects tested while blood alcohol levels (BAL) were(More)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is predominantly expressed in liver and regulates cholesterol metabolism by down regulating liver LDL receptor (LDLR) proteins. Here we report transgenic overexpression of human PCSK9 in kidney increased plasma levels of PCSK9 and subsequently led to a dramatic reduction in liver LDLR proteins. The(More)
In many of the theories of prediction and detection developed during the past decade, one encounters linear integral equations which can be subsumed under the general form j-2 w, 7) x(7) dT = f(f), a s f 6 b. This equation includes as special cases the Wiener-Hopf equation and the modified WienerHopf equation JOT R(j f 7 I) X(T) dr = f(f), 0 5 f 6 T. The(More)
The U.S. Environmental Protection Agency’s (EPA) Water Laboratory Alliance relies on the Centers for Disease Control and Prevention’s ultrafiltration-based Water Processing Procedure (WPP) for concentration of biosafety level 3 (BSL-3) agents from 10 L to 100 L of drinking water. The WPP requires comprehensive training and practice to maintain proficiency,(More)