Kenneth S. Kim

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Epigenetic histone modifications play an important role in the maintenance of different cell phenotypes. The exact molecular mechanism for inheritance of the modification patterns over cell generations remains elusive. We construct a Potts-type model based on experimentally observed nearest-neighbor enzyme lateral interactions and nucleosome covalent(More)
A long-time fluctuation correlation function with a power-law form has been observed in recent single-molecule experiments by the Xie group. By analyzing the dynamics of an elastic network model (ENM) under white noise, we show that the observed long-time memory kernel can be explained by the discrepancy between the experimentally measured coordinate (or(More)
Reconstruction of equations of motion from incomplete or noisy data and dimension reduction are two fundamental problems in the study of dynamical systems with many degrees of freedom. For the latter, extensive efforts have been made, but with limited success, to generalize the Zwanzig-Mori projection formalism, originally developed for hamiltonian systems(More)
Hang Zhang, Xiao-Jun Tian, Abhishek Mukhopadhyay, Kenneth S. Kim,Jianhua Xing1,4∗ Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, 24061-0406, USA Department of Physics, Virginia Tech, Blacksburg, Virginia, 24061-0406, USA Lawrence Livermore National Laboratory and University of California, Livermore, California, USA Beijing(More)
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