Kenneth R. Holmes

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Excretion and tissue retention of a coplanar and a non-coplanar hexachlorobiphenyl (HxCB) were determined 48 h after a single intraperitoneal (ip) dose of 8 mg/kg radiolabeled [14C]-HxCBs to weanling male and female Long-Evans rats. The objective was to understand the involvement of initial target organs of chlorobiphenyl (CB) accumulation following acute(More)
and were published in part previously. n The tabulation includes values for both the native thermal conductivity of biomaterials (Appendix A) and the blood perfusion rates for specific tissues and organs (Appendix B). Original sources are documented in the dedicated list of references at the end of each appendix. Knowledge of the perfusion behavior of(More)
The gross anatomy of the external genitalia of newborn to adult lesser Galago was described. The penis is perpendicular to the body wall at birth and by about 8 wk of age the testes have descended into the scrotum. In the adult male the testes are permanently descended, the scrotum sessile, the penis is oriented obliquely rostral, and the genitalia are(More)
PURPOSE To evaluate the relationship between both dynamic and steady-state measures of cerebrovascular reactivity (CVR) and the progression of age-related white matter disease. METHODS Blood oxygen level-dependent (BOLD) MRI CVR scans were acquired from forty-five subjects (age range: 50-90 years, 25 males) with moderate to severe white matter disease, at(More)
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