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As interventional procedures become more complicated, the need for accurate quantitative vascular information increases. In response to this need, many commercial vendors provide techniques for measurement of vessel sizes, usually based on derivative techniques. In this study, we investigate the accuracy of several techniques used in the measurement of(More)
Use of cone-beam computed tomography (CBCT) is becoming more frequent. For proper reconstruction, the geometry of the CBCT systems must be known. While the system can be designed to reduce errors in the geometry, calibration measurements must still be performed and corrections applied. Investigators have proposed techniques using calibration objects for(More)
PURPOSE To determine the effect of computer-aided diagnosis (CAD) on the accuracy of pulmonary nodule detection. MATERIALS AND METHODS Twenty abnormal chest radiographs, each with a single nodule, and 20 normal radiographs were digitized with a laser scanner. These images were analyzed by using a computer program that indicates areas that may represent(More)
The use of cone beam computed tomography (CBCT) is growing in the clinical arena due to its ability to provide 3D information during interventions, its high diagnostic quality (sub-millimeter resolution), and its short scanning times (60 s). In many situations, the short scanning time of CBCT is followed by a time-consuming 3D reconstruction. The standard(More)
We propose an optimization algorithm to solve the brachytherapy seed localization problem in prostate brachytherapy. Our algorithm is based on novel geometric approaches to exploit the special structure of the problem and relies on a number of key observations which help us formulate the optimization problem as a minimization integer program (IP). Our IP(More)
The use of cone beam computed tomography (CBCT) is growing in the clinical arena due to its ability to provide 3-D information during interventions, its high diagnostic quality (sub-millimeter resolution), and its short scanning times (60 seconds). In many situations, the short scanning time of CBCT is followed by a time consuming 3-D reconstruction. The(More)
PURPOSE Treatment of vascular disease often involves endovascular interventions which use the vascular system for delivering treatment devices via a previously inserted guidewire to the diseased site. Previous studies show relative reproducibility of guidewire position after insertion, indicating that the guidewire position is constrained and could be(More)
Construction of a cone-beam computed tomography (CBCT) system for laboratory research usually requires integration of different software and hardware components. As a result, building and operating such a complex system require the expertise of researchers with significantly different backgrounds. Additionally, writing flexible code to control the hardware(More)