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We review the literature on executing production schedules in the presence of unforeseen disruptions on the shop floor. We discuss a number of issues related to problem formulation, and discuss the functions of the production schedule in the organization and provide a taxonomy of the different types of uncertainty faced by scheduling algorithms. We then(More)
UBQLN1 variants have been associated with increased risk for late-onset Alzheimer's disease (AD). We produced transgenic Drosophila models that either silence (by RNAi) or overexpress the Drosophila ortholog of human UBQLN1, dUbqln. Silencing of dUbqln in the central nervous system led to age-dependent neurodegeneration and shortened lifespan. Silencing of(More)
BACKGROUND Heart failure is a debilitating condition resulting in severe disability and death. In a subset of cases, clustered as idiopathic dilated cardiomyopathy (iDCM), the origin of heart failure is unknown. In the brain of patients with dementia, proteinaceous aggregates and abnormal oligomeric assemblies of beta-amyloid impair cell function and lead(More)
I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. Abstract The facility layout design problem is a fundamental optimization problem encountered in many manufacturing(More)
As the popularity of wireless networks increases, so does the need to protect them. In recent years, many researchers have studied the limitations of the security mechanisms that protect wireless networks, as well as the effects of network traffic on the battery life. However, there has been less research on the effect of adding security mechanisms to(More)
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