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OBJECTIVE To prospectively and externally validate the Mortality in Emergency Department Sepsis (MEDS) score as a predictor of 28-day mortality in patients who present to the emergency department with a systemic inflammatory response syndrome. DESIGN Multicentered prospective cohort study. SETTING Emergency departments at the University of Colorado(More)
PURPOSE We sought to develop a temperature-based respiratory instrument to measure respiration noninvasively outside critical care settings. METHOD Respiratory temperature profiles were recorded using a temperature-based noninvasive instrument comprised of three rapid responding medical-grade thermistors-two in close proximity to the mouth/nose (sensors)(More)
STUDY OBJECTIVE To determine whether supplemental oxygen reduces the incidence of hypoxia by 20% in study patients receiving midazolam and fentanyl for emergency department procedural sedation and analgesia. METHODS Patients were randomized to receive either supplemental oxygen or compressed air by nasal cannula at 2 L per minute. Physicians were blinded(More)
STUDY OBJECTIVE We determine whether the use of capnography is associated with a decreased incidence of hypoxic events than standard monitoring alone during emergency department (ED) sedation with propofol. METHODS Adults underwent ED propofol sedation with standard monitoring (pulse oximetry, cardiac and blood pressure) and capnography and were(More)
We develop an approach to quantitative analysis of carbon dioxide concentration in exhaled breath, recorded as a function of time by capnography. The generated waveform--or capnogram--is currently used in clinical practice to establish the presence of respiration as well as determine respiratory rate and end-tidal CO 2 concentration. The capnogram shape(More)
STUDY OBJECTIVE We determine whether high-flow oxygen reduces the incidence of hypoxia by 20% in adults receiving propofol for emergency department (ED) sedation compared with room air. METHODS We randomized adults to receive 100% oxygen or compressed air at 15 L/minute by nonrebreather mask for 5 minutes before and during propofol procedural sedation. We(More)
STUDY OBJECTIVE We determine whether supplemental oxygen reduces the incidence of hypoxia by 20% compared with breathing room air in adult study patients receiving propofol for emergency department procedural sedation. METHODS Patients were randomized to receive either supplemental oxygen or compressed air by nasal cannula at 3 L per minute. Physicians(More)
We describe a case of a scapular abscess, osteomyelitis, septic emboli, and occlusive venous thrombosis secondary to community-acquired methicillin-resistant Staphylococcus aureus in an otherwise healthy pediatric patient. This syndrome represents a life-threatening condition that should ideally be recognized and treated in a timely fashion, not only with(More)
OBJECTIVE We used an emergency department (ED)-based method to provide targeted, individualized consultation; community notification; and public disclosure and collect data regarding willingness to participate in prospective resuscitation research requiring waiver of consent. METHODS We conducted a prospective survey of convenience cohort in an urban ED.(More)
BACKGROUND Oligoanalgesia challenges emergency department (ED) health care providers and remains an area of patient dissatisfaction. Nitrous oxide (NO) is a safe, quick-acting, and well-tolerated sedative agent with analgesic and anxiolytic properties that make it ideal for ED use. OBJECTIVES We seek to test the effectiveness of a self-administered and(More)