Kenneth Alibek

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More than one century passed since the viral cancerogenesis theory was declared. Enormous massive of new data on the role of viruses and viral constructions in cancer initiation and progression has been accumulated with the development of new diagnostic methods and biotechnology. The aim of this review was the analysis of current literature data on the(More)
This review concentrates on tumours that are anatomically localised in head and neck regions. Brain cancers and head and neck cancers together account for more than 873,000 cases annually worldwide, with an increasing incidence each year. With poor survival rates at late stages, brain and head and neck cancers represent serious conditions. Carcinogenesis is(More)
The most common cancer worldwide among women is breast cancer. The initiation, promotion, and progression of this cancer result from both internal and external factors. The International Agency for Research on Cancer stated that 18-20% of cancers are linked to infection, and the list of definite, probable, and possible carcinogenic agents is growing each(More)
Since the late 1990s, infectious agents have been thought to play a role in the pathogenesis of approximately 15% of cancers. It is now widely accepted that infection of stomach tissue with the bacteria Helicobacter pylori is an important cause of stomach adenocarcinoma. In addition, oncogenic viruses, such as papilloma viruses, herpes viruses, and(More)
The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries indicate that some viral proteins interfere with Bcl proteins either directly or indirectly; however, these data have not been(More)
All human herpesviruses (HHVs) have been implicated in immune system evasion and suppression. Moreover, two HHV family members, i.e. EBV and KSHV, are recognised as oncogenic viruses. Our literature review summarises additional examples of possible oncogenic mechanisms that have been attributed to other HHVs. In general, HHVs affect almost every(More)
Recent clinical and pre-clinical data demonstrate that adjuvant antimicrobial therapy is beneficial in cancer treatment. There could be several reasons for this effect, which include treating cancer associated bacteria and viruses, prophylaxis of post-chemotherapy infections due to immunosuppression, and antiproliferative effect of certain antimicrobials.(More)
PATIENT Female, 41 FINAL DIAGNOSIS: Ovarian carcinoma Symptoms: Ascites • hepatomegaly • weight loss MEDICATION - Clinical Procedure: - Specialty: Oncology. OBJECTIVE Unusual or unexpected effect of treatment. BACKGROUND The aim of this case report is to present the results of treatment of end-stage ovarian carcinoma in a 41-year-old women using(More)
We introduce the parameter of relevance of an attribute of a binary table to another attribute of the same table, computed with respect to an implicational basis of a closure system associated with the table. This enables a ranking of all attributes, by relevance parameter to the same fixed attribute, and, as a consequence, reveals the implications of the(More)