Kennedy W. Gilchrist

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Nonmalignant (n = 36) and malignant (n = 20) tissue samples were obtained from breast cancer and breast reduction surgeries. These tissues were characterized using multiple excitation wavelength fluorescence spectroscopy and diffuse reflectance spectroscopy in the ultraviolet-visible wavelength range, immediately after excision. Spectra were then analyzed(More)
BACKGROUND Fluorescence spectroscopy is an evolving technology that can rapidly differentiate between benign and malignant tissues. These differences are thought to be due to endogenous fluorophores, including nicotinamide adenine dinucleotide, flavin adenine dinucleotide, and tryptophan, and absorbers such as beta-carotene and hemoglobin. We hypothesized(More)
signatures in human cancers as a guide to targeted therapies. diffuse reflectance properties of malignant and benign breast tissues. Improvement in breast tumor discrimination by support vector machines and speckle-emphasis texture analysis. Automatic ultrasound segmentation and morphology based diagnosis of solid breast tumors.resolution aCGH and(More)
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