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Conventional burr-hole buttons sometimes do not fit the burr hole well due to the curvature of the surrounding bone. An irregular surface at the border between the button and the surrounding skull may appear unaesthetic. The major problem is the difference between the curvature radius of the skull and the burr-hole button in contact with the skull. To solve(More)
This study examines acoustic and articulatory EMA data of two female speakers (American and Japanese) spontaneously producing emotional speech while engaged in an informal telephone-type conversation. A set of control data in which the speakers imitated or read the original emotional utterance was also recorded; for the American speaker, the intonation(More)
This paper describes a new design rule checking system for LSI mask patterns. Major features of the system are a relatively small computing time needed, even for very large circuits (e.g. 10,000 elements), wide applications to a variety of fabrication processes, due to its functional flexibility, and minimized spurious errors.
The VCore [1](*) based design methodology, which has been developed at the VCDS (**) Project, is a SoC design methodology using VCores. A VCore is a reusable, high level abstracted design component. We have developed the VCore based design methodology and the VCDS tool prototype. We used the developed tool and did a trial SoC design. The design result(More)
A new LSI artwork analysis and processing system, called EMAP, is described with algorithms, a database schema and applications. EMAP provides the designer with the artwork verification and processing tools which include mask artwork processing, geometrical design rule checking, connectivity analysis and electrical circuit parameter calculation. The circuit(More)
This paper describes three programs which perform connectivity rule check, logic gate recognition for logic simulation and circuit connectivity comparison. These programs have been developed for verifying circuit connectivity extracted from mask artwork. Powerful algorithms are used in these programs, including a heuristic graph comparison algorithm, to(More)
In this paper, we will investigate the impacts of miniaturization of device dimensions that causes a paradigm shift in LSI design methodology. Major design issues in deep sub-micron LSIs, namely, wire delay , circuit complexity and power consumption will be discussed based on scaling theory. To resolve these issues , a concept called Layout Driven Synthesis(More)
Semaphorins are a family of secreted and membrane-bound proteins known as axonal pathfinders. Sema4A, a member of class 4 semaphorins, induces growth cone collapse of hippocampal neurons. The binding of Sema4A to growth cones indicates the presence of receptors transmitting signals through the intracellular effectors to induce growth cone collapse in(More)
BACKGROUND Chondrogenesis and subsequent endochondral ossification are processes tightly regulated by the transcription factor Sox9 (SRY-related high mobility group-Box gene 9), but molecular mechanisms underlying this activity remain unclear. Here we report that coactivator-associated arginine methyltransferase 1 (CARM1) regulates chondrocyte proliferation(More)