#### Filter Results:

- Full text PDF available (5)

#### Publication Year

2004

2017

- This year (1)
- Last 5 years (6)
- Last 10 years (7)

#### Publication Type

#### Co-author

#### Journals and Conferences

#### Key Phrases

Learn More

- Eri Ishikawa, Tetsuaki Ishikawa, +7 authors Sho Yamasaki
- The Journal of experimental medicine
- 2009

Tuberculosis remains a fatal disease caused by Mycobacterium tuberculosis, which contains various unique components that affect the host immune system. Trehalose-6,6'-dimycolate (TDM; also called cord factor) is a mycobacterial cell wall glycolipid that is the most studied immunostimulatory component of M. tuberculosis. Despite five decades of research on… (More)

- Yasunobu Miyake, Kenji Toyonaga, +9 authors Sho Yamasaki
- Immunity
- 2013

Cord factor, also called trehalose-6,6'-dimycolate (TDM), is a potent mycobacterial adjuvant. We herein report that the C-type lectin MCL (also called Clec4d) is a TDM receptor that is likely to arise from gene duplication of Mincle (also called Clec4e). Mincle is known to be an inducible receptor recognizing TDM, whereas MCL was constitutively expressed in… (More)

- Atsushi Furukawa, Jun Kamishikiryo, +8 authors Katsumi Maenaka
- Proceedings of the National Academy of Sciences…
- 2013

Mincle [macrophage inducible Ca(2+)-dependent (C-type) lectin; CLEC4E] and MCL (macrophage C-type lectin; CLEC4D) are receptors for the cord factor TDM (trehalose-6,6'-dimycolate), a unique glycolipid of mycobacterial cell-surface components, and activate immune cells to confer adjuvant activity. Although it is known that receptor-TDM interactions require… (More)

- Yoshio Ohtsubo, Kenji Toyonaga
- Math. Meth. of OR
- 2004

We consider eight problems in which we maximize or minimize threshold probabilities in discounted Markov decision processes with bounded reward set. We show that such problems are classified to two equivalence classes and give a relationship between optimal values and optimal policies of problems in each equivalence class. Literatures relative to such… (More)

- Kenji Toyonaga, Yasunobu Miyake, Sho Yamasaki
- PloS one
- 2014

Guinea pig is a widely used animal for research and development of tuberculosis vaccines, since its pathological disease process is similar to that present in humans. We have previously reported that two C-type lectin receptors, Mincle (macrophage inducible C-type lectin, also called Clec4e) and MCL (macrophage C-type lectin, also called Clec4d), recognize… (More)

- Kenji Toyonaga, Shota Torigoe, +18 authors Sho Yamasaki
- Immunity
- 2016

Phosphatidyl-inositol mannosides (PIM) are glycolipids unique to mycobacteria and other related bacteria that stimulate host immune responses and are implicated in mycobacteria pathogenicity. Here, we found that the FcRγ-coupled C-type lectin receptor DCAR (dendritic cell immunoactivating receptor; gene symbol Clec4b1) is a direct receptor for PIM.… (More)

- Etsuo SEGAWA, Kenji TOYONAGA, +5 authors Gary Greaves
- 2013

9:25 Opening Address from Chair 9:30 Spectral mapping theorem and asymptotic behavior of quantum walks on infinite graphs Etsuo SEGAWA (Tohoku Univ., JAPAN) 10:10 Tea Break 10:20 Seidel matrices with precisely three distinct eigenvalues Gary GREAVES (Tohoku Univ., JAPAN) 11:00 Tea Break 11:10 On the characteristic of a multiple eigenvalue of an Hermitian… (More)

For an Hermitian matrix whose graph is a tree and for a given eigenvalue having Parter vertices, the possibilities for the multiplicity are considered. If V = {v1, . . . , vk} is a fragmenting Parter set in a tree relative to the eigenvalue λ, and Ti+1 is the component of T−{v1, v2, . . . , vi} in which vi+1 lies, it is shown that k ∑ i Ni = mA(λ)+2k−1, in… (More)

- ‹
- 1
- ›