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BACKGROUND The etiology of oral squamous cell carcinoma (SCC) is still obscure. Since human papillomavirus (HPV) DNAs are associated with carcinoma of the uterine cervix, carcinomas of the oral cavity were investigated to ascertain if these viruses are present in squamous carcinomas of this anatomic site. METHODS Seventy-seven oral mucosal SCCs were(More)
Extended T-N Plane Abstraction (E-TNPA) proposed in this paper realizes work-conserving and efficient optimal real-time scheduling on multiprocessors relative to the original T-N Plane Abstraction (TNPA). Additionally a scheduling algorithm named NVNLF (No Virtual Nodal Laxity First) is presented for E-TNPA. E-TNPA and NVNLF relax the restrictions of TNPA(More)
Matrix metalloproteinases (MMPs) have been implicated in invasion and metastasis of tumor cells. Transcription regulatory regions of MMP genes often contain binding sites for ets transcription factors. We recently isolated a cDNA encoding human E1A-F, a member of the ets oncogene family, and showed that E1A-F can upregulate MMP genes by CAT assay. We(More)
Optimal real-time scheduling is effective to not only schedulability improvement but also energy efficiency for real-time systems. In this paper, we propose real-time static voltage and frequency scaling (RT-SVFS) techniques based on an optimal real-time scheduling algorithm for multiprocessors. The techniques are theoretically optimal when the voltage and(More)
E1AF is a newly identified human ets-family transcription factor. We have reported that E1AF can up-regulate transcription of matrix metalloproteinase (MMP) genes and confers invasive phenotype on human cancer cells. HSC3 is an oral squamous-cell-carcinoma-derived cell line, and it manifests high levels of E1AF and MMP-1 and -9 gene expression that are(More)
This paper proposes semi-fixed-priority scheduling to achieve both low-jitter and high schedulability. Semi-fixed-priority scheduling is for the extended imprecise computation model, which has a wind-up part as a second mandatory part and schedules the part of each extended imprecise task with fixed-priority. This paper also proposes a novel(More)
Modular component-based robot systems require not only an infrastructure for component management, but also scalability as well as real-time properties. Robot Technology (RT)-Middleware is a software platform for such component-based robot systems. Each component in the RT-Middleware, so-called ``RT-Component'' supporting particular robot functions, is(More)
Not only system performance but also energy efficiency is critically important for embedded systems. Optimal real-time scheduling is effective to not only schedulability improvement but also energy efficiency for the systems. In this paper, real-time dynamic voltage and frequency scaling (RT DVFS) techniques based on the theoretically optimal real-time(More)
p21(Waf1/Cip1) is one of the key regulatory proteins in cell cycle, terminal differentiation, and apoptosis. Its promoter was shown to be transactivated by the wild-type p53 protein as well as in a p53-independent manner. In this report, we demonstrate that E1AF, an ets-related transcription factor, activates the human p21(Waf1/Cip1) promoter by interacting(More)