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  • Yoshito Masamizu, Toshiyuki Ohtsuka, +5 authors Ryoichiro Kageyama
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2006 (First Publication: 31 January 2006)
  • Notch signaling components such as the basic helix-loop-helix gene Hes1 are cyclically expressed by negative feedback in the presomitic mesoderm (PSM) and constitute the somite segmentation clock.Continue Reading
  • Shigeki Yoshiura, Toshiyuki Ohtsuka, Yoshiko Takenaka, Hiroki Nagahara, Kenichi Yoshikawa, Ryoichiro Kageyama
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2007 (First Publication: 3 July 2007)
  • Serum response has been used as a model for studying signaling transduction for many biological events such as cell proliferation and survival. Although expression of many genes is up- orContinue Reading
  • Yuko Yoshikawa, Kohji Hizume, Yoshiko Oda, Kunio Takeyasu, Sumiko Araki, Kenichi Yoshikawa
  • Medicine, Chemistry
  • Biophysical journal
  • 2006 (First Publication: 1 February 2006)
  • Direct attack to genomic DNA by reactive oxygen species causes various types of lesions, including base modifications and strand breaks. The most significant lesion is considered to be an unrepairedContinue Reading
  • Shin-ichiro M. Nomura, Kanta Tsumoto, Tsutomu Hamada, Kazunari Akiyoshi, Yoichi Nakatani, Kenichi Yoshikawa
  • Medicine, Chemistry
  • Chembiochem : a European journal of chemical…
  • 2003 (First Publication: 7 November 2003)
  • Functional protein synthesis was observed in cell-sized lipid vesicles following encapsulation of a gene-expression system. Expression of rsGFP (red-shifted green fluorescent protein) withinContinue Reading