Kenichi Imamura

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OBJECTIVE It is believed that oxidative stress, which is provoked in patients with diabetes, plays critical roles in the pathogenesis of myocardial infarction (MI). We simultaneously determined 5 relatively common genetic variants related to oxidative stress and evaluated the combined effect on MI. METHODS We enrolled 3819 Japanese type 2 diabetic(More)
OBJECTIVE Adiponectin has anti-atherogenic properties and reduced serum adiponectin levels are associated with cardiovascular disease (CVD). In this study, we examined the relationship between CVD and adiponectin (ADIPOQ) gene G276T polymorphism that is associated with serum adiponectin level in a large cohort of type 2 diabetic patients. RESEARCH DESIGN(More)
We examined the association between diabetic retinopathy and monocyte chemoattractant protein (MCP)-1 A-2518G polymorphism in 3802 Japanese type 2 diabetic subjects. The prevalence of diabetic retinopathy was higher as the number of G alleles increased, suggesting that the G allele of this polymorphism is a susceptibility allele for diabetic retinopathy.
The estimated theoretical limit to oscillation frequency predicts that the frequency of a GaAs monolithic astable multiviblator type oscillator can be increased from the maximum reported frequency of 5 GHz to 17 GHz by optimization of circuit parameters. The increase is made possible by the W-silicide self alignment process due to its precision processing(More)
It is expected that endoscopy in the primary mass screening of stomach cancer is effective in the detection of the early gastric cancer, though it would be accompanied by many difficulties. For the purpose of surmizing its accuracy and the effective follow-up interval, diagnostic results of all endoscopic examinations which had been done from 1970 to 1976(More)
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